Acantholysis: Loss of cohesion between epidermal cells (keratinocytes) with consequent formation of intra-epidermal spaces containing oedema fluid and detached, rounded epithelial cells.
Acanthosis: Thickening of the epidermis either focally or diffusely, due largely to increase of the stratum malpighii (Stratum Spinosum and Stratum Basali)
Dyskeratosis: Premature, abnormal or individual keratinisation of epidermal cells: the cells that loose their prickles and become rounded off, and the nucleus becomes pyknotic. This is seen in some rare benign conditions but more commonly in pre-malignant lesions and carcinoma of the epidermis.
Acantholysis, Acanthosis, Dyskeratosis
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Acantholysis: Loss of cohesion between epidermal cells (keratinocytes) with consequent formation of intra-epidermal spaces containing oedema fluid and detached, rounded epithelial cells.
ReplyDeleteAcanthosis: Thickening of the epidermis either focally or diffusely, due largely to increase of the stratum malpighii (Stratum Spinosum and Stratum Basali)
Dyskeratosis: Premature, abnormal or individual keratinisation of epidermal cells: the cells that loose their prickles and become rounded off, and the nucleus becomes pyknotic. This is seen in some rare benign conditions but more commonly in pre-malignant lesions and carcinoma (CANCER) of the epidermis.